MEBT was invented on the basis of a series of burns natural pathogeneses, appreciating each aspects of burns tissue’s physiological response including physical, chemical and biochemical reactions.

Additionally, it incorporates an understanding of necrotic tissue rejection as well as principles of physiological repair and regeneration. 

The main therapeutic focus is manifested in the following aspects:

1. Alleviation of wound pain by microprotection of injured nerve ending and by relief of hair arrectores pilorum spasm; 

2. Prevention or resolution of continuous physical thermal injury by the application of an ointment which draws away the residual heat from the wound through a specially designed frame structure dosage;

3. Discharge of necrotic tissues by liquefaction without causing further secondary injury while allowing the residual viable tissues to continue an endogenous process of regeneration;

4. Creation of a physiologically moist environment to ensure the physiological repair of residual skin tissues;

5. Realization of skin regeneration in compliance with the principles of endogenous histological and cyto-logical regeneration; 

6. Control of microbial concentration and toxicity at the wound site so as to prevent and control pathogenic infection through continuous active drainage of the wound as well as by other mechanisms; 

7. Regulation of the physiological repair of burns wounds with the comprehensive active ingredients of the MEBO ointment.

Burns regenerative medicine and therapy (MEBT/ MEBO) was established in the context of a worldwide consensus that surgical burns therapy comprised a subop-timal therapy. 

It arose in a therapeutic vacuum where no substantial innovations had been offered for modern burns treatment.

MEBT/MEBO has basically realized the treatment of burns tissue itself, and become the mainstream medical therapy for skin burns. 

However, even MEBT/MEBO has its limitations, for presently it also is not suitable for treating burns involving muscle or deeper layers.

Unfortunately, current research has made no progress in regenerating new skin from muscle tissue. 

For burns with a diameter less than 20 cm involving the muscle layer, the wound may heal with MEBT/MEBO by the migrating of epithelial cells from the wound margin transversely to regenerate skin and then close the wound.

With the assistance of a surgical technique, electric burns and local burns involving bones may be treated with satisfactory results (data attached below). 

Happily, burns replacement therapy offers a breakthrough therapeutic benefit in that it may enable larger muscle layer burns to heal spontaneously.