Directly smear MEBO onto the wounds with a thickness of 1 mm. 

At the beginning, no debridement is required except for chemical burns or dirty wounds. 

Renew MEBO every 3–4 h, before which wiping off the residual ointment and liquefaction products with gauze or tissue paper (gentle and careful renewal is demanded to avoid pains and bleeding). 

1. For wounds with blisters, be sure to preserve the blister skin, directly apply MEBO until the blister skin is removed 5 days later. 

2. For deep second-degree burns, after applying MEBO, dermal tissue in the necrotic layer begins to liquefy on day 7 postburn. 

Renew MEBO and wipe off the liquefaction product timely. 

After the complete discharge of necrotic tissue, apply less MEBO and renew every 4–6 h till the wounds heal. 

3. For third-degree burns, treatment with a special debridement technique can be applied coordinately.