Bedsore ulcers, which are common in patients with debility, paralysis and long-term lay-up, refer to the tissue necrosis and ulceration due to long-term pressure on skin blood vessels and nerves, which damages local blood circulation and results in nutritional disturbance.

The key points in decubital treatment are as follows: 

1. treat the primary disease actively, 
2. strengthen the basic nurse, 
3. enhance the resistance of the body, 
4. control wound infection, 
5. keep wound drained unobstructedly, 
6. ameliorate local microcirculation, 
7. and accelerate tissue regeneration and restoration [2].

Li SL [3] used exposed and binding-up therapies to treat 15 cases of bedsore ulcers with different depth and course in different parts with MEBO. All the patients were healed without toxicity and side reactions. 

Zhang SC etc. [4] immerged the antiseptic gauzes into warmed MEBO to make MEBO gauzes, and covered the bedsore wound or filled sinus tracts. The drug and dressing were changed once or twice a day. All the 5 cases were healed. 

Chen ZY etc. [5] used MEBO to treat 32 cases of bedsore ulcer, and observed the changes in wound, the bacterial culture results of wound, and scars after the wounds were healed. They thought MEBO had strong anti-infection capacity, and could improve local microcirculation, reduce scar formation, and had no influence on the functional restoration of the functional parts. 

Kong Jun [6] treated 60 cases of bedsore ulcers due to different causal factors in different parts with bandaging therapy. The cure rate after 2 months was 78.3%, and the cure rate after 6 months reached 96.7%.

References:

2. Liu F. Practical Dermatology [M]. Second edition, Beijing: The People's Medical Publishing Company. 1996, 25: p. 264-277.
3. Li S. Clinical Analysis On The 15 Bedsore Cases Treated With MEBO [J]. The Chinese Journal of Burns Wounds & Surface Ulcers. 1998, (4): p. 38.
4. Zhang S., Liu Z. Experience of Using MEBO to Treat Third-degree Bedsores [J]. The Chinese Journal of Burns Wounds & Surface Ulcers. 1999, (1): p. 33-34.
5. Chen Z., Wang Y. Experience of Using MEBO to Treat 32 Bedsore Cases [J]. The Chinese Journal of Burns Wounds & Surface Ulcers. 2001, 12(3): p. 188-189.
6. Kong J. Experience of Using MEBO to Treat 60 PhaseⅢ Senile Bedsore Cases [J]. The Chinese Journal of Burns Wounds & Surface Ulcers. 2002, 14 (1): p. 34-35.
7. Qi F. Treatment Of Refractory Chronic Skin Ulcer [J]. Chinese Clinical